Research articles

Sepulveda G, Antkowiak M, Brust-Mascher I, Mahe K, Ou T, Castro N, Christensen LN, Cheung L, Jiang X, Yoon D, Huang B, and Jao LE (2018). Co-translational protein targeting facilitates centrosomal recruitment of PCNT during centrosome maturation in vertebrates. eLife 2018;7:e34959 DOI: 10.7554/eLife.34959 [Other version: bioRxiv doi:]


Susman MW, Karuna EP, Kunz RC, Gujral TS, Cantú AV, Choi SS, Jong BY, Okada K, Scales MK, Hum J, Hu LS, Kirschner MW, Nishinakamura R, Yamada S, Laird DJ, Jao LE, Gygi SP, Greenberg ME, and Ho HH (2017). Kinesin superfamily protein Kif26b links Wnt5a-Ror signaling to the control of cell and tissue behaviors in vertebrates. eLife. 2017 Sep 8;6. pii: e26509. doi: 10.7554/eLife.26509.


Jao LE*, Akef A, and Wente SR (2017). A role for Gle1, a regulator of DEAD-box RNA helicases, at centrosomes and basal bodies. Molecular Biology of the Cell 28: 120-127.

*Corresponding author


Liu LY, Lin MH, Lai ZY, Jiang JP, Huang YC, Jao LE, and Chuang YJ (2016). Motor neuron-derived Thsd7a is essential for zebrafish vascular development via the Notch-dll4 signaling pathway. Journal of Biomedical Science 23: 59-69.


Kaneb HM, Folkmann AW, Belzil VV, Jao LE, Leblond CS, Girard SL, Daoud H, Noreau A, Rochefort D, Hince P, Szuto A, Vidal S, André-Guimont C, Camu W, Bouchard JP, Dupré J, Meininger V, Rouleau GA, Wente SR, and Dion PA (2015). Deleterious mutations in the essential mRNA metabolism factor, hGle1, in amyotrophic lateral sclerosis. Human Molecular Genetics 24: 1363-1373.


Jao LE, Wente SR, and Chen W (2013). Efficient multiplex biallelic zebrafish genome editing using a CRISPR nuclease system. Proceedings of the National Academy of Sciences USA 110: 13904-13909.


Varshney GK, Lu J, Gildea DE, Huang H, Pei W, Yang Z, Huang SC, Schoenfeld D, Pho N, Diaz-Cano DC, Hirase T, Moshbrook-Davis D, Zhang S, Jao LE, Zhang B, Wolfsberg TG, Pellegrini M, Burgess SM, and Lin S (2013). A large-scale zebrafish gene knockout resource for the genome-wide study of gene function. Genome Research 23: 727-735.


Jao LE, Appel B, and Wente SR (2012). A zebrafish model of lethal congenital contracture syndrome 1 reveals Gle1 function in spinal neural precursor survival and motor axon arborization. Development 139: 1316-1326.


Wang D*, Jao LE*, Zheng N, Dolan K, Ivey J, Zonies S, Wu X, Wu K, Yang H, Meng Q, Zhu Z, Zhang B, Lin S, and Burgess SM (2007). Efficient genome-wide mutagenesis of zebrafish genes by retroviral insertions. Proceedings of the National Academy of Sciences USA 104: 12428-12433.

*Equal contributions


Jao DL and Chen KY (2006). Tandem affinity purification revealed the hypusine-dependent binding of eukaryotic initiation factor 5A to the translating 80S ribosomal complex. Journal of Cellular Biochemistry 97: 583-598.


Xu A, Jao DL, and Chen KY (2004). Identification of mRNA that binds to eukaryotic initiation factor 5A by affinity co-purification and differential display. Biochemical Journal 384: 585-590.


Jao DL and Chen KY (2002). Subcellular localization of the hypusine-containing eukaryotic initiation factor 5A by immunofluorescent staining and green fluorescent protein tagging. Journal of Cellular Biochemistry 86: 590-600.





Book Chapters

Yin L, Jao LE, and Chen W (2015). Generation of targeted mutations in zebrafish using the CRISPR/Cas System. Methods in Molecular Biology 1332: 205-217.

Jao LE and Burgess SM (2009). Production of pseudotyped retrovirus and the generation of proviral transgenic zebrafish. Methods in Molecular Biology 546: 13-30.






Jao LE, Maddison LA, Chen W, and Burgess SM (2008). Using retroviruses as the mutagenesis tool to explore the zebrafish genome. Briefings in Functional Genomics 7: 427-443.


Chen KY and Jao DL (1999). Chemistry of hypusine formation on eukaryotic initiation factor 5A in biological systems. Journal of the Chinese Chemical Society 46: 727-734.


The complete list of publications can be found here.

Jao Lab | UC Davis School of Medicine | Department of Cell Biology and Human Anatomy

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